In an SN2 reaction the configuration at the reacting carbon atom is

  • A. inverted, because the nucleophile attacks from the side opposite the leaving group
  • B. retained completely
  • C. randomised, giving a racemic mixture
  • D. unchanged because no bond is broken

Explanation

Back side attack turns the three remaining groups inside out like an umbrella in the wind, so an optically active substrate gives a product of opposite configuration, an effect called Walden inversion. An SN1 reaction gives a racemic mixture instead, because the planar carbocation can be attacked equally from either face. Stereochemistry is therefore the clearest experimental way to distinguish the two mechanisms.

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