Asked in PMC Practice Test 3 (2022) 2022Moderate

In aldol condensation, the nucleophile is _.

Correct answer: C. Carbanion

  • A. Hydroxyl ion
  • B. Carbocation
  • C. Carbanion
  • D. Water

Explanation

The reaction mechanism below shows that the carbanion is the nucleophile of the reaction:

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About Nucleophilic Addition Reactions

Nucleophilic addition occurs at the polar carbonyl group of aldehydes and ketones, where a nucleophile attacks the electron-deficient carbon atom. Reactions with hydrogen cyanide, sodium bisulfite, alcohols and Grignard reagents are explained through tetrahedral intermediates, acid or base catalysis, and the different reactivity of aldehydes and ketones.

Practise Aldehydes and Ketones

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