How does praziquantel mainly affect adult cestodes in a treated animal?
Correct answer: A. It increases calcium permeability
- A. It increases calcium permeability
- B. It blocks folate synthesis
- C. It inhibits beta-tubulin assembly
- D. It paralyses nematode muscle by opening chloride channels
Explanation
Praziquantel increases calcium permeability in the tegument and muscle of cestodes, causing contraction, paralysis, and damage to the parasite surface. Inhibition of beta-tubulin is associated with benzimidazoles, while chloride-channel effects are typical of ivermectin.
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