How does ivermectin mainly paralyse susceptible nematodes?
Correct answer: A. It opens glutamate-gated chloride channels
- A. It opens glutamate-gated chloride channels
- B. It blocks bacterial cell-wall synthesis
- C. It inhibits fungal ergosterol formation
- D. It prevents protozoal folate production
Explanation
Ivermectin increases chloride ion entry through glutamate-gated chloride channels in parasite nerve and muscle cells, causing paralysis. The other mechanisms describe antibacterial, antifungal, or antiprotozoal drug actions.
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Covers the recognition, diagnosis, prevention and medical treatment of diseases affecting domestic animals, including infectious, metabolic, nutritional, toxic and organ-system disorders. It links history taking, physical examination, clinical signs, laboratory findings and differential diagnosis with appropriate therapy and herd or flock control.
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