Hexokinase plays a role in:
Correct answer: C. Glycolysis
- A. Krebs cycle
- B. Electron transport chain
- C. Glycolysis
- D. Pyruvate oxidation
Explanation
Glycolysis is a metabolic pathway that occurs in the cytoplasm of cells and is responsible for the breakdown of glucose into two molecules of pyruvate. It is the first step in cellular respiration and is a central pathway for glucose metabolism. Hexokinase plays a crucial role in the early steps of glycolysis. The reaction catalyzed by hexokinase in glycolysis is as follows: Glucose + ATP → Glucose-6-phosphate + ADP. In this step, hexokinase phosphorylates glucose using ATP as a phosphate donor, producing glucose-6-phosphate and ADP. This phosphorylation of glucose is essential for trapping glucose inside the cell and initiating its metabolism.
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About Bioenergetics
Cellular respiration explains how cells release energy from glucose through glycolysis, the link reaction, Krebs cycle and electron transport chain. It includes ATP production, substrate-level and oxidative phosphorylation, aerobic versus anaerobic respiration, and the roles of mitochondria, oxygen and fermentation in energy transfer.
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