Heme is converted to bilirubin mainly in_____________?
Correct answer: C. Spleen
- A. Kidney
- B. Liver
- C. Spleen
- D. Bone marrow
Explanation
Heme is broken down mainly by macrophages of the reticuloendothelial system, especially those in the spleen, forming biliverdin and then bilirubin. The liver mainly conjugates and excretes the bilirubin rather than forming most of it.
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