Gastric secretion has been shown to be most effectively reduced with the use of___________?

Correct answer: B. H2 histamine receptor antagonist

  • A. H1 histamine receptor antagonist
  • B. H2 histamine receptor antagonist
  • C. Adrenal steroids
  • D. Anticholinergic

Explanation

H2-receptor antagonists directly block histamine-stimulated acid secretion by gastric parietal cells and reduce basal and meal-stimulated secretion. H1 antagonists mainly treat allergic conditions, not gastric hypersecretion.

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