Extreme change in pH results in which of the following?
Correct answer: D. Denaturation of the enzymes
- A. Change in ionization of amino acids at the active site of the enzyme
- B. Change in the ionization of the substrate
- C. Increase in the rate of reaction
- D. Denaturation of the enzymes
Explanation
Enzymes are affected by changes in pH. The most favorable pH value - the point where the enzyme is most active - is known as the optimum pH. The change in pH will lead to the ionization of amino acid atoms and molecules, changing the shape and structure of proteins, thus damaging the function of the enzyme and denaturing it. The ultimate change due to change in pH will be denaturation.
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About Enzymes
Enzymes are biological catalysts that lower activation energy without being consumed, and their specificity is explained by the lock and key and induced fit models. Work includes the effects of temperature, pH and substrate concentration on reaction rate, plus competitive and non-competitive inhibition and how these differ.
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