Endotoxic shock is propagated____________?
Correct answer: B. Cytokine action
- A. Endothelial injury
- B. Cytokine action
- C. Increased vascular permeability
- D. Peripheral vasodilation
Explanation
Endotoxin stimulates macrophages and other cells to release cytokines such as TNF and IL-1, initiating vasodilation, endothelial activation and increased permeability. Thus, cytokine action is the primary propagating mechanism, even though the other changes follow.
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