Endocrine cells of duodenum are stimulated by _____ to release hormone secretin.
Correct answer: B. Acidic chyme
- A. Acetylcholine
- B. Acidic chyme
- C. Bile salts
- D. Sodium bicarbonate in bile juice
Explanation
Acidic chyme entering the duodenum stimulates its endocrine cells to release secretin, which makes the pancreas secrete bicarbonate to neutralise the acid. Sodium bicarbonate is the result of secretin action rather than its trigger, and bile salts and acetylcholine do not stimulate secretin release.
This question appeared on the UHS MDCAT 2026 paper, which you can sit online with every answer explained.
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