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During transcription, holoenzyme RNA polymerase binds to a DNA sequence, and the DNA assumes a saddle-like structure at that point. What is that sequence called?

Correct answer: B. TATA box

  • A. AAAT box
  • B. TATA box
  • C. GGTT box
  • D. CAAT box

Explanation

The DNA sequence that holoenzyme RNA polymerase binds to during transcription, and the DNA assumes a saddle-like structure at that point, is called the TATA box. The TATA box is a consensus sequence, meaning that it is a sequence of nucleotides that is found in the promoter region of many eukaryotic genes. It is located about 10 base pairs upstream of the transcription start site. The TATA box is important for transcription because it helps to position the RNA polymerase in the correct place to start transcription. It also helps to recruit other transcription factors that are necessary for transcription to occur.The other options are incorrect because:AAAT is not a consensus sequence for the promoter region of eukaryotic genes.GGTT is not a consensus sequence for the promoter region of eukaryotic genes.CAAT is a consensus sequence for the CAAT box, which is another important promoter element, but it is not the sequence that RNA polymerase binds to to initiate transcription.

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