During replication, which sequence of nucleotides would bond with the DNA sequence TATGA
Correct answer: D. ATACT
- A. AUAGA
- B. ATACA
- C. UAUGU
- D. ATACT
Explanation
Nucleotides are the building blocks of nucleic acids, i.e., DNA and RNA. A nucleotide consists of a sugar molecule attached to a phosphate group and a nitrogen-containing base. The bases used in DNA are adenine (A), cytosine (C), guanine (G), and thymine (T). While in RNA, thymine (T) is replaced by uracil (U). The bases present on the two strands of DNA pair through hydrogen bonds in a specific manner. Following the above rules, T is complementary to A A is complementary to T T is complementary to A G is complementary to C A is complementary to T Thus the strand complementary to the strand containing TATGA bases should contain ATACT bases.
This question appeared on the ETEA MDCAT 2011 paper, which you can sit online with every answer explained.
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About Structure of DNA
DNA structure includes nucleotides made of deoxyribose, phosphate and nitrogenous bases, arranged in two antiparallel polynucleotide strands. Questions cover the double helix, phosphodiester and hydrogen bonds, complementary base pairing between adenine and thymine and between guanine and cytosine, and the significance of major and minor grooves.
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