Dry mouth during antidepressant therapy is caused by blockade of______________?
Correct answer: A. Muscarinic acetylcholine receptors
- A. Muscarinic acetylcholine receptors
- B. Serotonergic receptors
- C. Dopaminergic receptors
- D. GABA receptors
Explanation
Many antidepressants, especially tricyclics, cause dry mouth by blocking muscarinic acetylcholine receptors and reducing salivary secretion. Serotonergic, dopaminergic and GABA receptor blockade does not explain this classic anticholinergic effect.
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