Denaturation of a protein involves
Correct answer: B. loss of its three dimensional shape while the amino acid sequence remains intact
- A. hydrolysis of all its peptide bonds
- B. loss of its three dimensional shape while the amino acid sequence remains intact
- C. a change in its amino acid sequence
- D. conversion of the protein into a carbohydrate
Explanation
Heat, extreme pH, heavy metal ions and alcohol break the weak interactions holding the fold, so the chain unravels and biological activity is lost, but the covalent peptide backbone survives. This is why a boiled egg sets irreversibly without breaking down into amino acids. Hydrolysis of the peptide bonds is digestion, a different process requiring enzymes or prolonged heating with acid.
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About Importance of Proteins
Proteins are polymers of amino acids joined by peptide bonds, and their biological roles depend on primary, secondary, tertiary and quaternary structure. Coverage includes enzymes, hormones, antibodies, transport proteins, muscle fibres and structural tissues, together with denaturation and the effects of heat, pH and chemicals.
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