Carbamazepine has been utilized to successfully diminish attacks in trigeminal neuralgia. During this therapy which of the following is indicated ?
Correct answer: B. Clinical observation and complete blood and platelet counts prior to and at frequent intervals during therapy
- A. Clinical observation only
- B. Clinical observation and complete blood and platelet counts prior to and at frequent intervals during therapy
- C. No monitoring
- D. Complete blood investigation only if adverse symptoms arise
Explanation
Carbamazepine can rarely cause bone-marrow suppression, including leukopenia, thrombocytopenia, and aplastic anemia. A baseline complete blood count with platelet count and repeated monitoring is therefore indicated.
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