Brittle bone syndrome is caused by______________?
Correct answer: A. Improper synthesis of procollagen
- A. Improper synthesis of procollagen
- B. Polymerisation of collagen
- C. Increase osteoclastic activity
- D. Increase fibroblastic activity
Explanation
Brittle bone syndrome, or osteogenesis imperfecta, results from defective type I collagen production, commonly involving abnormal procollagen synthesis. Increased osteoclastic activity is not the primary defect.
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