Attachment of Okazaki fragments to DNA's lagging strand is facilitated by:
Correct answer: A. Ligase
- A. Ligase
- B. Polymerase III
- C. Polymerase II
- D. DNAase
Explanation
Ligase is responsible for sealing the nicks between adjacent Okazaki fragments by catalyzing the formation of phosphodiester bonds. It joins the 3' hydroxyl group of one fragment to the 5' phosphate group of the adjacent fragment, thereby creating a continuous strand of DNA.
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Chromosomes are DNA-protein structures that carry genes and become visible during cell division. Coverage includes chromatin, centromeres, sister chromatids, homologous chromosomes, chromosome number, and the distinction between diploid and haploid cells, with links to DNA replication, mitosis and meiosis.
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