Moderate

At the beginning of translation, a tRNA molecule carrying a chemically modified _ binds to the _:

Correct answer: A. Methionine, Small ribosomal subunit

  • A. Methionine, Small ribosomal subunit
  • B. Methionine, Large ribosomal subunit
  • C. Tyrosine, Large ribosomal subunit
  • D. Tyrosine, Small ribosomal subunit

Explanation

In prokaryotes polypeptides synthesis begins with the formation of the initiation complex. First, the tRNA molecule carrying a chemically modified methionine (called N-formyl methionine) binds to the small ribosomal subunit. A protein called the initiation factor positions the tRNA on the ribosomal surface at the P side, where the peptide bond is formed.

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