Antibody-dependent cellular cytotoxicity against an antibody-coated target cell is commonly performed by:
Correct answer: D. Natural killer cells
- A. Basophils
- B. Erythrocytes
- C. Naive B cells
- D. Natural killer cells
Explanation
Natural killer cells bind the Fc portion of target-bound IgG through CD16 and then release cytotoxic granules. This process is called antibody-dependent cellular cytotoxicity, or ADCC.
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About Veterinary Microbiology and Immunology
Covers the structure, classification, growth and transmission of bacteria, viruses, fungi and other disease causing microorganisms in animals. It explains innate and acquired immunity, antibodies, antigens, vaccination, hypersensitivity and diagnostic methods, while distinguishing infectious agents from the immune responses they produce.
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