An untoward effect of that is common to all phenothiazines is______________?
Correct answer: B. Rigidity and tremor at rest, particularly with prolonged use
- A. A marked increase in blood pressure
- B. Rigidity and tremor at rest, particularly with prolonged use
- C. Suppression of prolacin
- D. Nausea
Explanation
Phenothiazines can block dopamine receptors in the nigrostriatal pathway, producing extrapyramidal effects such as rigidity and resting tremor, particularly with prolonged treatment. They generally increase rather than suppress prolactin, and marked hypertension is not a class-wide effect.
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