All the following about antiemetic drugs are correct except_______________?
Correct answer: D. Ondastran may cause vomiting by effecting the cytotoxic antige receptors
- A. Domperidone blocks the D2 receptors in CTZ and upper gut
- B. Domperidone causes Dystonia
- C. Ondastran acts on selective 5 -HT3 receptors
- D. Ondastran may cause vomiting by effecting the cytotoxic antige receptors
Explanation
Ondansetron blocks 5-HT3 receptors and prevents, rather than causes, vomiting associated with cytotoxic therapy. Domperidone mainly acts peripherally at D2 receptors, while dystonia is uncommon but possible, especially at higher exposure.
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