All of the following statements are true regarding the attachment or adsorption of the virion to the host cell EXCEPT that?
Correct answer: D. All of the above.
- A. For naked virions, the surface capsid proteins are responsible for binding to a specific cell receptor.
- B. For enveloped viruses, the spikes are responsible for binding to a specific cell receptor.
- C. cell lacking a receptor for a specific virus is not infected by that virus.
- D. All of the above.
Explanation
.The surface of capsid protein is responsible for binding to a specific cell receptor in naked virions. The capsid of a virus is the protein shell that encloses the viral genome, and it plays a critical role in the viral life cycle, including the process of viral entry into host cells. The surface of the capsid is often decorated with proteins that can bind to specific receptors on the surface of host cells, allowing the virus to attach to and enter the cell. In the case of naked virions, which lack an envelope, the surface of the capsid is the primary site of interaction with host cells, and the capsid proteins are responsible for binding to specific cell receptors. The spikes on the envelope of enveloped viruses are often responsible for binding to specific cell receptors. The envelope of a virus is a lipid membrane that surrounds the capsid and is studded with proteins, including spikes, which are often involved in the process of viral entry into host cells. The spikes on the envelope can bind to specific receptors on the surface of host cells, allowing the virus to attach to and enter the cell. The specific spikes that are involved in this process can vary depending on the virus, but they are often essential for viral entry and pathogenesis. If a cell lacks a receptor for a specific virus, it is less likely to be infected by that virus. The ability of a virus to infect a host cell depends on a variety of factors, including the presence of specific receptors on the surface of the cell that the virus can recognize and bind to. If a cell does not have the appropriate receptor for a given virus, the virus may not be able to enter the cell and replicate. However, it is important to note that some viruses can evolve to use alternative receptors or entry pathways, which can allow them to infect a broader range of cell types. Additionally, not all viruses require specific receptors to enter cells, and some may be able to enter cells through other mechanisms, such as by fusing directly with the cell membrane. All the options are correct so the correct option is D.
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About Viruses
Viruses are acellular infectious particles made of genetic material enclosed by a protein capsid, sometimes with a lipid envelope. Their replication depends on a host cell and may follow lytic or lysogenic cycles, so viral structure and reproduction differ fundamentally from those of cellular organisms such as bacteria.
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