Asked in Premeth Test 18 — Alkyl Halides, Aldehydes and Ketones, Atomic Structure (20 March 2025) 2025Moderate

Acetophenone can be formed by which of the following reaction for benzene?

Correct answer: B. Acylation

  • A. Alkylation
  • B. Acylation
  • C. Halogenation
  • D. Nitration

Explanation

Benzene can be converted to acetophenone (methyl phenyl ketone) by Friedel-Crafts acylation. Firstly, we react ethanoyl chloride with aluminum trichloride (AlCl3) to obtain the electrophile 'CH3C+=O'. The electrophile, when provided with the correct conditions, in the presence of benzene, will undergo a substitution reaction to form acetophenone.

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About Benzene and Aromatic Compounds

Benzene has a planar ring of delocalised π electrons, giving aromatic stability and equal carbon-carbon bond lengths. The topic covers resonance, electrophilic substitution reactions such as nitration, halogenation, sulphonation and Friedel-Crafts reactions, along with substituent effects and the distinction between substitution in benzene and addition in ordinary alkenes.

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