According to the widely accepted "fluid mosaic model" cell membranes are semi-fluid, where lipids and integral proteins can diffuse randomly. In recent years, this model has been modified in several respects. In this regard, which of the following statements is incorrect?
Correct answer: A. Proteins can also undergo flip-flop movements in the lipid bilayer
- A. Proteins can also undergo flip-flop movements in the lipid bilayer
- B. Many proteins remain completely embedded within the lipid bilayer
- C. Proteins in cell membranes can travel within the lipid bilayer
- D. Proteins can remain confined within certain domains of the membranes
Explanation
The incorrect statement is A. In the fluid mosaic model, proteins are generally considered to be too large to undergo spontaneous flip-flop movements in the lipid bilayer. Instead, they can undergo lateral diffusion within the membrane.An improved model of the structure of cell membrane was proposed by Singer and Nicolson (1972) widely accepted as fluid mosaic model. According to this, the quasi-fluid nature of lipid enables lateral movement (Flip-flop) of proteins within the overall bilayer. This ability to move within the membrane is measured as its fluidity.
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