A patient with severe hypotension from septic shock remains unstable after appropriate intravenous fluid resuscitation. Which vasoactive medicine is generally used as the first-line vasopressor?

Correct answer: A. Norepinephrine

  • A. Norepinephrine
  • B. Isosorbide dinitrate
  • C. Furosemide
  • D. Propranolol

Explanation

Norepinephrine produces mainly alpha-adrenergic vasoconstriction and supports vascular tone in persistent septic shock. Isosorbide dinitrate and furosemide can reduce effective circulation, while propranolol can worsen hypotension and bradycardia.

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Emergency pharmacology covers drugs used in cardiac arrest, shock, severe allergy, acute asthma, seizures, poisoning and hypoglycaemia, including adrenaline, atropine, naloxone, flumazenil and selected antidotes. The focus is on indications, routes, rapid adverse effects, dose safety and matching a toxic substance with its specific reversal agent.

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