A patient taking sertraline and linezolid becomes restless and confused and develops sweating, fever, diarrhoea, and muscle clonus. Which nursing action is most appropriate?
Correct answer: B. Withhold serotonergic medicines and notify the prescriber urgently
- A. Administer the next sertraline dose with additional water
- B. Withhold serotonergic medicines and notify the prescriber urgently
- C. Encourage exercise to reduce restlessness and improve sleep
- D. Give an over-the-counter cough medicine for symptom relief
Explanation
This presentation is consistent with serotonin syndrome caused by excessive serotonergic activity. Sertraline and other contributing medicines should be withheld as prescribed, and urgent assessment is needed because hyperthermia, rigidity, and organ damage may develop. Some cough medicines, especially those containing dextromethorphan, can worsen serotonergic toxicity.
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About Psychopharmacology
Psychopharmacology covers the actions, uses, adverse effects, and nursing responsibilities associated with antipsychotics, antidepressants, mood stabilizers, anxiolytics, sedatives, and stimulants. It includes extrapyramidal symptoms, tardive dyskinesia, neuroleptic malignant syndrome, serotonin syndrome, lithium toxicity, medication adherence, and monitoring of therapeutic response.
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