A patient taking rifampicin begins using combined oral contraceptive pills. Which teaching is most appropriate?
Correct answer: A. Rifampicin can reduce contraceptive effectiveness
- A. Rifampicin can reduce contraceptive effectiveness
- B. The contraceptive will increase rifampicin toxicity
- C. The two medicines always improve each other's action
- D. Rifampicin prevents all menstrual side effects
Explanation
Rifampicin induces hepatic drug-metabolising enzymes and can reduce the effectiveness of combined oral contraceptives. The patient should discuss reliable additional or alternative contraception with the prescriber.
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About Principles of Pharmacology
Pharmacology examines drug sources, names, dosage forms, mechanisms of action, absorption, distribution, metabolism and excretion. Questions cover pharmacokinetics versus pharmacodynamics, therapeutic effects, adverse reactions, contraindications, drug interactions, tolerance, dependence and the safety responsibilities of the nurse.
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