A patient receiving amphotericin B develops a rising serum creatinine level. Which adverse effect does this finding suggest?
Correct answer: A. Nephrotoxicity from the antifungal drug
- A. Nephrotoxicity from the antifungal drug
- B. Ototoxicity from the antifungal drug
- C. Retinal toxicity from the antifungal drug
- D. Severe hypoglycemia from the antifungal drug
Explanation
Amphotericin B can cause significant renal impairment and electrolyte disturbances, so renal function and electrolytes require monitoring. Hearing loss, retinal injury and hypoglycemia are not its characteristic major toxicities.
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About Antimicrobial Drugs
Antimicrobial pharmacology covers antibiotics, antitubercular, antifungal, antiviral and antiparasitic drugs, including their targets, clinical uses, resistance and major adverse effects. Questions distinguish bactericidal from bacteriostatic action, narrow from broad spectrum therapy, and antimicrobial treatment from supportive management of infection.
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