A disease caused by an autosomal primary non-disjunction is:
Correct answer: D. Down's syndrome
- A. Klinefelter's syndrome
- B. Turner's syndrome
- C. Sickle cell anaemia
- D. Down's syndrome
Explanation
Down syndrome is trisomy 21, an autosomal nondisjunction event producing an extra chromosome 21. Klinefelter and Turner involve sex chromosomes; sickle cell is single-gene.
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About Inheritance
Mendel's laws explain segregation, independent assortment and the prediction of genetic ratios using alleles, genotypes and phenotypes. The chapter also covers linked genes, recombination and crossing over during meiosis, then applies pedigree reasoning to X-linked recessive traits, which show different inheritance patterns in males and females.
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