Which therapeutic effect is expected from amlodipine in a patient with hypertension?

Correct answer: A. Relaxation of arterial smooth muscle and lower vascular resistance

  • A. Relaxation of arterial smooth muscle and lower vascular resistance
  • B. Increased sodium retention and expanded circulating volume
  • C. Reduced clotting factor production and slower thrombus formation
  • D. Increased bronchial smooth muscle contraction and airway narrowing

Explanation

Amlodipine is a calcium channel blocker that mainly relaxes arteriolar smooth muscle, reducing systemic vascular resistance and blood pressure. It does not act as an anticoagulant or bronchodilator, and sodium retention is not its intended effect.

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About Cardiovascular and Respiratory Drugs

Cardiovascular and respiratory drugs include antihypertensives, diuretics, antianginal agents, antiarrhythmics, cardiac glycosides, anticoagulants, bronchodilators, corticosteroids and cough medicines. Questions focus on mechanisms, indications, contraindications, toxicity and monitoring, especially the difference between drugs that reduce blood pressure, improve cardiac output or open narrowed airways.

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