Asked in PMC Practice Test 28 (2021) 2021Moderate

Which structure of protein gives information about the folding of a protein?

Correct answer: B. Tertiary structure

  • A. Primary structure
  • B. Tertiary structure
  • C. Secondary structure
  • D. Quaternary structure

Explanation

The tertiary structure is the overall folding of the polypeptide chain, and it is determined by the interactions between the side chains of the amino acids. These interactions include ionic and disulfide bonds. The tertiary structure gives information about the folding of the protein. Whereas, the primary structure is the sequence of amino acids in the polypeptide chain. The secondary structure is the local folding patterns of the polypeptide chain, such as alpha helices and beta sheets. Lastly, the quaternary structure of a protein is the arrangement of multiple polypeptide chains in a single protein molecule. This is carried about by the hydrophobic interactions between the polypeptide chains.

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About Proteins

Proteins are polymers of amino acids joined by peptide bonds, and their function depends on primary, secondary, tertiary and quaternary structure. The topic covers fibrous and globular proteins, enzymes, antibodies, hormones and transport proteins, as well as denaturation by heat or extreme pH.

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