Which statement is incorrect about the Lock and Key Model?
Correct answer: D. It explains the mechanism of every chemical reaction.
- A. Specific enzyme can transform only a specific substrate.
- B. Active site of an enzyme is a non-flexible structure.
- C. Active site does not change before during or even after the reaction.
- D. It explains the mechanism of every chemical reaction.
Explanation
The lock-and-key model describes enzyme-substrate interactions, suggesting that enzymes and substrates have specific complementary shapes that fit perfectly together. Enzymes are highly specific and must bind to a substrate to catalyze a reaction. Enzymes following this model are non-regulatory. However, this model doesn't explain all chemical reactions, making option D correct. Evidence indicates that enzymes can change shape upon substrate binding, supporting the induced fit model as a more accurate representation of enzyme-substrate interactions.
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About Enzymes
Enzymes are biological catalysts that lower activation energy without being consumed, and their specificity is explained by the lock and key and induced fit models. Work includes the effects of temperature, pH and substrate concentration on reaction rate, plus competitive and non-competitive inhibition and how these differ.
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