Which of the following statements is not true for retroviruses?
Correct answer: A. DNA is not present at any stage in the life cycle of retroviruses.
- A. DNA is not present at any stage in the life cycle of retroviruses.
- B. Retroviruses carry gene for RNA dependent DNA polymerase.
- C. The genetic material in mature retroviruses is RNA.
- D. Retroviruses are causative agents for ertain kinds of cancer in man.
Explanation
a) "DNA is not present at any stage in the life cycle of retroviruses" - This statement is not true. Retroviruses have a unique life cycle that involves the conversion of their RNA genome into DNA. They carry the gene for reverse transcriptase, an enzyme that allows them to synthesize a DNA copy of their RNA genome once they infect a host cell. This DNA form is integrated into the host cell's genome.b) "Retroviruses carry the gene for RNA-dependent DNA polymerase" - This statement is true. Retroviruses carry the gene for reverse transcriptase, which is also known as RNA-dependent DNA polymerase. This enzyme is responsible for transcribing the viral RNA into DNA.c) "The genetic material in mature retroviruses is RNA" - This statement is true. Retroviruses store their genetic information as RNA. However, during the replication process, they reverse transcribe this RNA into DNA, which becomes integrated into the host cell's genome.d) "Retroviruses are causative agents for certain kinds of cancer in man" - This statement is true. Some retroviruses are known to be oncogenic, meaning they can cause cancer in humans. For example, the human T-cell lymphotropic virus type 1 (HTLV-1) is associated with the development of adult T-cell leukemia (a form of cancer).Summary: The correct answer is option A. Retroviruses do have DNA at some stages in their life cycle, specifically in the form of a DNA copy of their RNA genome, which is integrated into the host cell's genome. This process is mediated by reverse transcriptase (RNA-dependent DNA polymerase). Retroviruses are indeed linked to certain types of cancer in humans.
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