Which of the following statement is incorrect regarding germ theory of diseases postulated by Robert Koch?

Correct answer: D. The pure culture cannot produce the disease when inoculated into susceptible animal.

  • A. A specific organism can always be found in association with a given disease
  • B. The organism can be isolated and grown in pure culture in the laboratories
  • C. It is possible to recover the organism in pure culture from the experimentally infected animals.
  • D. The pure culture cannot produce the disease when inoculated into susceptible animal.

Explanation

Koch's fourth postulate states that the pure culture of the isolated microorganism should be capable of reproducing the disease when inoculated into a healthy, susceptible animal. This step is essential to establish a cause-and-effect relationship between the microorganism and the disease. If the cultured microorganism does not produce the disease when introduced into a healthy animal, it raises doubts about its role in causing the disease.

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