Which of the following statement about fatigue is correct?

Correct answer: D. All of these

  • A. The major event in it is accumulation of lactic acid.
  • B. Lactic acid accumulation turns pH in acidic range leading to muscle ache.
  • C. Ionic imbalance may also cause it.
  • D. All of these

Explanation

Muscle fatigue may involve lactate and hydrogen ion accumulation, changes in pH, and ionic disturbances that interfere with excitation and contraction, so all the listed mechanisms are accepted at this level. The likely distractor is option a or b if a student treats one mechanism as the only cause of fatigue.

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