Which of the following proteins play a functional role in creating the force-tension curve of muscle contraction?
Correct answer: D. All of these
- A. Titin
- B. Myosin
- C. Actin
- D. All of these
Explanation
Option D is correct since the force-tension curve/ length-tension curve describes the maximum isometric force, a muscle generates, as sarcomere lengths vary. As muscle is stretched from extremely short to extremely long lengths, the force it generates increases over the ascending limb, peaks in the plateau region, and decreases over the descending limb. So, the sequence of events occurring in the muscle contraction influences sarcomere shortening.Option A is incorrect since it only states one out of the three correct answers. Titan is a mechanical protein in muscle cells that has the main function as a molecular spring in the contractile units, the sarcomeres.Option B is incorrect since it only states one out of the three correct answers. The myosin heads bind to actin and cause the actin filaments to slide. Finally, ATP breaks the actin-myosin bond and allows another myosin 'oar stroke' to occur. Repetition of these events causes a muscle to contract.Option C is incorrect since it only states one out of the three correct answers. Muscle contraction thus results from an interaction between the actin and myosin filaments that generates their movement relative to one another. The molecular basis for this interaction is the binding of myosin to actin filaments, allowing myosin to function as a motor that drives filament sliding.
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About Support and Movement
Support and movement covers the axial and appendicular skeleton, bone structure, joints and the arrangement of skeletal muscles. Muscle contraction is explained through actin, myosin, sliding filaments, calcium ions and ATP, while arthritis is distinguished as a disorder of joints rather than a normal part of movement.
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