Which of the following is true about tetanus acquired through traumatic wound ?
Correct answer: A. Clostridium tetani travels via the nerves to the anterior horn dells in spinal cord
- A. Clostridium tetani travels via the nerves to the anterior horn dells in spinal cord
- B. The tetanospasmin component of the exotoxin act on the post-synaptic neurones and prevents impulse transmission
- C. The patient should be given tetanus toxoid intravenously
- D. Causes positive Nagler reaction
Explanation
Tetanospasmin travels by retrograde axonal transport to the spinal cord, where it blocks inhibitory interneuron function and causes muscle spasm. Tetanus toxoid is given intramuscularly, and the Nagler reaction is associated with Clostridium perfringens, not C. tetani.
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