Which of the following is true about bradykinin?
Correct answer: A. It is produced at the site of tissue injury.
- A. It is produced at the site of tissue injury.
- B. It has no role in the leakage of fluids into the tissues in inflammation.
- C. It destroys phagocytes.
- D. It produces interferon gamma.
Explanation
Bradykinin is a peptide hormone that plays a key role in the inflammatory response. It is produced at the site of tissue injury, where it is generated from kininogen by the action of kallikrein. Bradykinin then binds to specific receptors on blood vessels and other cells, leading to:- Increased vascular permeability (leakage of fluids into tissues)- Smooth muscle contraction- Pain transmission- Inflammation
This question appeared on the KMU MDCAT 2023 (retake) paper, which you can sit online with every answer explained.
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