Which of the following is an inactive enzyme without its cofactor?

Correct answer: B. Apoenzyme

  • A. Coenzyme
  • B. Apoenzyme
  • C. Holoenzyme
  • D. Denatured enzyme

Explanation

The correct answer is apoenzyme. An apoenzyme is the protein part of an enzyme that is inactive on its own. It requires the presence of a cofactor to become a holoenzyme, which is the active form. In contrast, a coenzyme is a type of cofactor, not an enzyme, and a holoenzyme is an enzyme with its cofactor attached, making it active. A denatured enzyme is one that has lost its functional shape and activity due to external factors, not due to the absence of a cofactor.

This question appeared on the ETEA MDCAT 2006 paper, which you can sit online with every answer explained.

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About Characteristics of Enzymes

Enzymes are globular biological catalysts that lower activation energy without being consumed, usually showing specificity for particular substrates. Questions cover active sites, enzyme substrate complexes, the lock and key and induced fit models, intracellular and extracellular action, and the effects of denaturation, while distinguishing enzymes from non biological catalysts.

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