Which of the following carboxylic acid derivative is least reactive?
Correct answer: C. Acid amide
- A. Acyl halide
- B. Acid anhydride
- C. Acid amide
- D. Ester
Explanation
Option C is correct.Acid amides are the least reactive carboxylic acid derivatives. They are least reactive because the nitrogen atom in the amide group is a poor leaving group.The nitrogen atom in the amide group is not easily removed from the molecule. Acyl chloride>anhydride>ester=carboxylic acid>amide>carboxylate ion
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About Carboxylic Acids
Carboxylic acids are named and studied through the combined effects of the carbonyl and hydroxyl groups, their preparation, acidity and hydrogen bonding. Reactions include neutralisation, esterification, reduction and conversion into acid chlorides, anhydrides, esters and amides, with emphasis on how these derivatives interconvert.
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