Which is associated with defect in DNA repair___________?

Correct answer: A. Xeroderma pigmentosum

  • A. Xeroderma pigmentosum
  • B. Albinism
  • C. Icthyosis
  • D. Sickle cell anaemia

Explanation

Xeroderma pigmentosum results from defective nucleotide-excision repair of ultraviolet-induced DNA damage, causing extreme photosensitivity and skin cancers. Albinism affects melanin production, while sickle-cell anaemia is caused by a haemoglobin mutation.

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