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Which instruction is correct for a patient taking alendronate for osteoporosis?

Correct answer: B. Take it with plain water and remain upright

  • A. Take it with milk before going to bed
  • B. Take it with plain water and remain upright
  • C. Take it with calcium at the same time
  • D. Crush it and mix it with fruit juice

Explanation

Alendronate is taken with plain water on an empty stomach, and the patient remains upright to reduce oesophageal irritation and improve absorption. Calcium, milk, juice and other medicines can reduce its absorption.

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Endocrine pharmacology includes insulin preparations, oral antidiabetic drugs, thyroid and antithyroid medicines, corticosteroids, sex hormones and drugs affecting calcium balance. Questions address onset and duration, administration, monitoring, hypoglycaemia, steroid adverse effects and the difference between replacing a deficient hormone and suppressing excessive hormone activity.

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