Which among the following anti-histamines, is Least likely to cause sedation_____________?
Correct answer: D. Loratidine
- A. Promethazine
- B. Diphenhydramine
- C. Hydroxyzine
- D. Loratidine
Explanation
Loratadine is a second-generation H1 antihistamine with poor penetration into the central nervous system, so it causes much less sedation. Promethazine, diphenhydramine, and hydroxyzine are first-generation agents and are more sedating.
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