Which action best describes the main glucose-lowering effect of metformin?
Correct answer: B. It reduces hepatic glucose production
- A. It stimulates pancreatic insulin release
- B. It reduces hepatic glucose production
- C. It replaces circulating thyroid hormone
- D. It blocks intestinal fat absorption
Explanation
Metformin primarily decreases glucose production by the liver and improves insulin sensitivity. It does not directly replace insulin or thyroid hormone, and its use alone has a low risk of hypoglycaemia.
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About Endocrine and Diabetes Drugs
Endocrine pharmacology includes insulin preparations, oral antidiabetic drugs, thyroid and antithyroid medicines, corticosteroids, sex hormones and drugs affecting calcium balance. Questions address onset and duration, administration, monitoring, hypoglycaemia, steroid adverse effects and the difference between replacing a deficient hormone and suppressing excessive hormone activity.
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