Asked in NUMS 2019 (cancelled sitting) 2019Moderate

When the muscle is required to contract, calcium ion binds with _ molecule and causes them to move slightly.

Correct answer: C. Troponin

  • A. Actin
  • B. Myosin
  • C. Troponin
  • D. Tropomyosin
  • E. ATP

Explanation

Troponin is a complex of three proteins that are involved in muscle contraction. When calcium ions bind to the troponin complex, it causes a change in the complex that moves the tropomyosin molecule slightly, exposing the myosin-binding sites on the actin filament. This allows the myosin head to bind to the actin filament, sliding the actin and myosin filaments past each other, leading to muscle contraction.

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About Muscle Contraction

Muscle contraction is explained by the sliding filament model, in which myosin heads pull actin filaments within sarcomeres using ATP. The topic covers calcium, troponin, tropomyosin, the neuromuscular junction and relaxation, with attention to how filament length stays almost constant while the sarcomere shortens.

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