Type I hypersensitivity is mediated by which of the following immunoglobulins ?
Correct answer: D. IgE
- A. IgA
- B. IgG
- C. IgM
- D. IgE
Explanation
Type I hypersensitivity is driven by allergen-specific IgE, which binds mast cells and basophils and triggers mediator release on re-exposure. IgG and IgM are more characteristic of antibody-mediated Type II reactions.
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