Asked in Premeth past paper pool — BiologyModerate

Troponin is one of the major proteins in the thin (actin) filaments of muscle fibres.It is a complex made up of three polypeptides with three binding sites for

Correct answer: C. Actin, tropomyosin and calcium ions

  • A. Myosin, actin and ATP
  • B. Actin, tropomyosin and ATP
  • C. Actin, tropomyosin and calcium ions
  • D. Myosin, tropomyosin and calcium ions

Explanation

The correct answer is that troponin has binding sites for actin, tropomyosin, and calcium ions. Troponin is a regulatory protein that plays a crucial role in muscle contraction by binding to these three components. When calcium ions bind to troponin, it induces a conformational change that allows tropomyosin to move away from actin's active sites, enabling myosin to bind to actin and initiate contraction. ATP is not directly involved in the binding with troponin; rather, it provides energy for muscle contraction. Myosin is not directly bound by troponin either, as its interaction is mainly with actin. Hence, options A, B, and D are incorrect.

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About Muscle Contraction

Muscle contraction is explained by the sliding filament model, in which myosin heads pull actin filaments within sarcomeres using ATP. The topic covers calcium, troponin, tropomyosin, the neuromuscular junction and relaxation, with attention to how filament length stays almost constant while the sarcomere shortens.

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