Total number of linkage groups in a normal human is:
Correct answer: B. 23
- A. 02
- B. 23
- C. 46
- D. 92
Explanation
All the genes on one chromosome form a single linkage group, and the number of linkage groups equals the haploid chromosome number, which for humans is 23. The figure 46 is the diploid number, counting both members of each homologous pair, but the two homologues carry the same set of loci and so form one group, not two. Ninety two would be the count of chromatids after replication.
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About Gene Linkage and Crossing Over
Linked genes lie on the same chromosome and tend to pass together, unlike genes that assort independently on different chromosomes. The topic connects linkage with homologous pairing, crossing over during prophase I of meiosis, recombinant and parental offspring, and recombination frequency as an estimate of gene distance.
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