This locks the HIV genome into the capsid:
Correct answer: A. Gag protein
- A. Gag protein
- B. Env protein
- C. Pol protein
- D. All of these
Explanation
The HIV Gag protein is responsible for packaging and locking the viral genome inside the capsid because its nucleocapsid (NC) domain specifically binds the RNA packaging signal (Ψ) and tethers the genome during assembly, while its capsid (CA) domain polymerizes to form the protective shell. In contrast, Pol encodes enzymes (protease, reverse transcriptase, and integrase) that are co-packaged but do not mediate genome encapsidation, and Env forms the envelope glycoproteins for viral entry, playing no role in capsid assembly or RNA packaging.
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Biological classification uses taxonomic ranks, binomial nomenclature and shared characteristics to organize life into kingdoms. The major groups include prokaryotes, protists, fungi, plants and animals, with comparisons based on cell type, cell wall, nutrition, body organization, reproduction and evolutionary relationships; prokaryotes lack a membrane-bound nucleus.
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