Thiamine deficiency can be diagnosed by measuring________________?
Correct answer: B. Transketolase activity in RBC
- A. Thiamine levels in blood
- B. Transketolase activity in RBC
- C. Alkaline phosphatase levels in blood
- D. Plasma pyruvate and lactic acid levels
Explanation
Thiamine pyrophosphate is required by erythrocyte transketolase, so reduced transketolase activity is a useful functional test for thiamine deficiency. Blood thiamine concentration is less reliable for detecting tissue deficiency.
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